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Article

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

27 Mar 2019

Abstract excerpt

The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed a lifelong history of painless injuries, such as frequent cuts and burns, which were observed to heal quickly. We...

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Identifiers

PMID: 30929760
DOI: 10.1016/j.bja.2019.02.019

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