Article
Rapid screening for potentially relevant polymorphisms in the human fatty acid amide hydrolase gene using Pyrosequencing.
Prostaglandins & other lipid mediators - 1 Nov 2007
Doehring Alexandra, Geisslinger Gerd, Lötsch Jörn
Abstract excerpt
INTRODUCTION: Fatty acid amides such as the endocannabinoid anandamide serve as mammalian lipid transmitters in various physiological and pathophysiological processes including inflammation. They are rapidly degraded by the fatty acid amide hydrolase (FAAH). Non-functional FAAH resulted in reduced inflammatory and nociceptive responses. Evidence suggests that human genetic FAAH variants modulate pain and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
