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Article

Out of the dark: the emerging roles of lncRNAs in pain.

Trends in genetics : TIG - 1 Aug 2024

Habib Abdella M, Cox James J, Okorokov Andrei L

Abstract excerpt

The dark genome, the nonprotein-coding part of the genome, is replete with long noncoding RNAs (lncRNAs). These functionally versatile transcripts, with specific temporal and spatial expression patterns, are critical gene regulators that play essential roles in health and disease. In recent years, FAAH-OUT was identified as the first lncRNA associated with an inherited human pain insensitivity disorder. Several...

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PMID: 38926010
DOI: 10.1016/j.tig.2024.04.009

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