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Article

Iron overload and liver cancer

18 Mar 2019

Abstract excerpt

, Muto et al. (https://doi.org/10.1084/jem.20180900) generate a novel mouse model of liver cancer induced by iron overload by deleting the iron-sensing ubiquitin ligase FBXL5 specifically in hepatocytes and exposure to a chemical carcinogen.

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Share to Endoplasmic Reticulum Stress and Disease
Share to Ferroptosis and cancer prognosis
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Identifiers

PMID: 30886060
DOI: 10.1084/jem.20190257

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