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Article

Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2.

Carcinogenesis - 1 Jun 2016

Karin Michael, Dhar Debanjan

Abstract excerpt

The liver is a key metabolic organ that is essential for production of blood proteins, lipid and sugar metabolism and detoxification of naturally occurring and foreign harmful chemicals. To maintain its mass and many essential functions, the liver possesses remarkable regenerative capacity, but the latter also renders it highly susceptible to carcinogenesis. In fact, liver cancer often develops in the context of...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27207669
DOI: 10.1093/carcin/bgw060
PMCID: PMC4876993

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