Article
Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma.
American journal of human genetics - 4 Feb 2016
Cheng Caixia, Zhou Yong, Li Hongyi, Xiong Teng, Li Shuaicheng, Bi Yanghui, Kong Pengzhou, Wang Fang, Cui Heyang, Li Yaoping, Fang Xiaodong, Yan Ting, Li Yike, Wang Juan, Yang Bin, Zhang Ling, Jia Zhiwu, Song Bin, Hu Xiaoling, Yang Jie, Qiu Haile, Zhang Gehong, Liu Jing, Xu Enwei, Shi Ruyi, Zhang Yanyan, Liu Haiyan, He Chanting, Zhao Zhenxiang, Qian Yu, Rong Ruizhou, Han Zhiwei, Zhang Yanlin, Luo Wen, Wang Jiaqian, Peng Shaoliang, Yang Xukui, Li Xiangchun, Li Lin, Fang Hu, Liu Xingmin, Ma Li, Chen Yunqing, Guo Shiping, Chen Xing, Xi Yanfeng, Li Guodong, Liang Jianfang, Yang Xiaofeng, Guo Jiansheng, Jia JunMei, Li Qingshan, Cheng Xiaolong, Zhan Qimin, Cui Yongping
Abstract excerpt
Comprehensive identification of somatic structural variations (SVs) and understanding their mutational mechanisms in cancer might contribute to understanding biological differences and help to identify new therapeutic targets. Unfortunately, characterization of complex SVs across the whole genome and the mutational mechanisms underlying esophageal squamous cell carcinoma (ESCC) is largely unclear. To define a...
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