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IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway

28 Mar 2023

Abstract excerpt

Interferon (IFN) helps cells fight viral infections by further inducing the expression of many downstream IFN-stimulated genes (ISGs). Human interferon-inducible transmembrane proteins (IFITM) are one of these ISGs. The antiviral function of human IFITM1, IFITM2, and IFITM3 are well known. In this study, we report that IFITM can significantly inhibit EMCV infectivity in HEK293 cells. Overexpression of IFITM...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37112847
DOI: 10.3390/v15040866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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