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Article

Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma

23 Jan 2019

Abstract excerpt

Mutant TP53 is a promising therapeutic target in cancers. Considering the current challenges facing the clinical treatment of cancer, as well as the urgent need to identify novel therapeutic targets in osteosarcomas, we aimed to evaluate the clinical significance of mutant TP53 in osteosarcoma patients and to explore the therapeutic effect of targeting mutant TP53 in osteosarcomas. We performed a meta-analysis to...

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PMID: 30667081
DOI: 10.1002/jor.24227

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