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Article

CD44 Contributes to the Regulation of MDR1 Protein and Doxorubicin Chemoresistance in Osteosarcoma

3 Aug 2022

Abstract excerpt

Osteosarcoma is the most common type of pediatric bone tumor. Despite great advances in chemotherapy during the past decades, the survival rates of osteosarcoma patients remain unsatisfactory. Drug resistance is one of the main reasons, leading to treatment failure and poor prognosis. Previous reports correlated expression of cluster of differentiation 44 (CD44) with drug resistance and poor survival of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35955749
DOI: 10.3390/ijms23158616

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