Molecular pathogenesis of osteosarcoma.

Abstract excerpt

Osteosarcoma is a devastating but rare disease, whose study has illuminated both the basic biology and clinical management of cancer over the past 30 years. These contributions have included insight into the roles of key cancer genes such as the retinoblastoma tumor suppressor gene and TP53, the identification of familial cancer syndromes implicating DNA helicases, and dramatic improvements in survival by the use...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bloom Syndrome
• Share to Matrix Metalloproteinases
• Share to Neurofibromin 2