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Article

Early-life undernutrition reprograms CD4+ T-cell glycolysis and epigenetics to facilitate asthma

15 Jan 2019

Abstract excerpt

Background Exposure to early-life undernutrition is closely related to higher risks of adverse immunologic outcomes in adulthood. Although it has been suggested that asthma has its origins in early life, its underlying mechanisms remain largely unknown. Objective We characterized the effects of early-life undernutrition on T lymphocytes, which play a pivotal role in immune diseases, and we investigated whether...

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Share to Asthma and respiratory diseases
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 30654047
DOI: 10.1016/j.jaci.2018.12.999

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