Article

Metabolic and functional impairment of CD8 <sup>+</sup> T cells from the lungs of influenza-infected obese mice

2020-04-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Obesity increases influenza disease risk in millions of adults worldwide. In this study, we investigated the effect of diet-induced obesity on pulmonary CD8 + T cell metabolism and function as a mechanism of impairment. <h4>Methods</h4> Male C57BL/6J mice were fed either control (10% kcal/g) or high-fat (60% kcal/g) diet. Sub-lethal A/PR/8/34 influenza virus infection gen...

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Literature Corpus work: c878c440-e54f-545a-b2f7-a2d69a62bfda
DOI: 10.1101/2020.04.19.047282

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