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Article

Longitudinal association between astrocyte function and glucose metabolism in autosomal dominant Alzheimer’s disease

4 Dec 2018

Abstract excerpt

The spatial resolution of 18 F-fluorodeoxyglucose PET does not allow the specific cellular origin of its signal to be determined, but it is commonly accepted that transport and trapping of 18 F-fluorodeoxyglucose reflects neuronal glucose metabolism. The main frameworks for the diagnosis of Alzheimer’s disease suggest that hypometabolism measured with 18 F-fluorodeoxyglucose PET is a biomarker of neuronal injury...

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PMID: 30515545
DOI: 10.1007/s00259-018-4217-7

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