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Article

The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes

4 Dec 2018

Abstract excerpt

Mitochondrial dynamics refers to the constant remodeling of mitochondrial populations by multiple cellular pathways that help maintain mitochondrial health and function. Disruptions in mitochondrial dynamics often lead to mitochondrial dysfunction, which is frequently associated with disease in rodents and humans. Consistent with this, obesity is associated with reduced mitochondrial function in white adipose...

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PMID: 30512991
DOI: 10.1152/ajpendo.00394.2018

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