Article

CRISPR screens reveal ZBTB17/MIZ1 as a peroxisome regulator

2024-07-26

Abstract excerpt

<h4>ABSTRACT</h4> Peroxisomes are integral metabolic organelles involved in both catabolic and anabolic processes in humans, with defects often linked to diseases. The functions of peroxisomes are regulated at transcriptional, translational, and post-translational levels. In this study, we employed the CRISPR/Cas9-based genetic screening of a ubiquitin ligase library to identify regulators of human peroxisomes. W...

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Literature Corpus work: e724cb2d-a544-545c-94b2-925179a06eba
DOI: 10.1101/2024.07.25.605214

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