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Article

Quantitative characterization of tumor cell-free DNA shortening.

BMC genomics - 10 Jul 2020

Guo Juntang, Ma Kefeng, Bao Hua, Ma Xiangyuan, Xu Yang, Wu Xue, Shao Yang W, Jiang Mei, Huang Jin

Abstract excerpt

BACKGROUND: Previous studies found that cell-free DNA (cfDNA) generated from tumors was shorter than that from healthy cells, and selecting short cfDNA could enrich for tumor cfDNA and improve its usage in early cancer diagnosis and treatment monitoring; however, the underlying mechanism of shortened tumor cfDNA was still unknown, which potentially limits its further clinical application. RESULTS: Using targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32650715
DOI: 10.1186/s12864-020-06848-9
PMCID: PMC7350596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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