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Article

Identification of HLA-DQA1 and HLA-DRB5 as Risk Factors for Multiple Sclerosis: An Epigenome-Wide Methylation Haplotype Association Analysis.

International journal of immunogenetics - 1 Jun 2026

Shang Zhenwei, Wang Jiacheng, Xu Jing, Zhang Mingming, Lv Hongchao, Jiang Yongshuai, Zhang Ruijie, Lv Wenhua

Abstract excerpt

Multiple sclerosis (MS) is a chronic central nervous system inflammatory disease of autoimmune aetiology. The disease is mostly considered due to a complex interaction between different genetic and environmental factors. DNA methylation is an epigenetic mechanism that can influence gene expression and has the potential to mediate the effects of environmental factors on MS. This study aimed to identify MS risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41728745
DOI: 10.1111/iji.70043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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