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Article

Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jul 2014

Graves M C, Benton M, Lea R A, Boyle M, Tajouri L, Macartney-Coxson D, Scott R J, Lechner-Scott J

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is thought to be caused by T-cell mediated autoimmune dysfunction. Risk of developing MS is influenced by environmental and genetic factors. Modifiable differences in DNA methylation are recognized as epigenetic contributors to MS risk and may provide a valuable link between environmental exposure and inherited genetic systems. OBJECTIVES AND METHODS: To identify methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24336351
DOI: 10.1177/1352458513516529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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