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Article

Methylation Profiles of IL33 and CCL26 in Bronchial Epithelial Cells are Associated with Asthma

23 Nov 2018

Abstract excerpt

AIM: This study aimed to characterize DNA methylation (DNA-me) in promoter region of IL33, IL1RL1 and CCL26 in asthma and their impacts on transcriptional activity in bronchial epithelial cells (BECs). PATIENTS & METHODS: We performed bis-pyrosequencing, quantitative real-time PCR and sequencing in BECs from ten asthmatic and ten control individuals. RESULTS: We detected lower DNA-me levels of IL33 and CCL26 in...

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Identifiers

PMID: 30468398
DOI: 10.2217/epi-2018-0044

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