Article
DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children.
PloS one - 1 Jan 2012
Stefanowicz Dorota, Hackett Tillie-Louise, Garmaroudi Farshid S, Günther Oliver P, Neumann Sarah, Sutanto Erika N, Ling Kak-Ming, Kobor Michael S, Kicic Anthony, Stick Stephen M, Paré Peter D, Knight Darryl A
Abstract excerpt
BACKGROUND: Allergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis. However, the genetic, environmental or epigenetic factors involved in these conditions are likely to be different. Epigenetic modifications, such as DNA methylation, can be influenced by the environment and result in changes to gene expression. OBJECTIVES: To...
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