Article
Lack of a transcriptional response of primary bronchial epithelial cells from patients with asthma and controls to IL-33
5 Dec 2023
Abstract excerpt
The IL-33/IL-1RL1 pathway stands as a formidable genetic predisposition for asthma, with ongoing clinical developments of various drugs designed to mitigate its influence in patients with asthma. The absence of a transcriptomic reaction to IL-33 within the bronchial epithelium holds significance in the pursuit of identifying biomarkers that can aid in pinpointing those individuals who would derive the greatest...
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