Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study between IL-33 gene DNA methylation and Pediatric asthma.

International immunopharmacology - 1 Apr 2026

Zhang Yali, Yan Lei, Li Zhumei, Li Bo, Yu Yiyi, Meng Wenjuan, Zhu Xiaoping

Abstract excerpt

OBJECTIVE: Investigate IL-33 gene DNA methylation, its relationship with serum Th2 immune factors, and the rs4742170 SNP in childhood asthma, analyzing genetic, environmental, and epigenetic factors in asthma risk. METHODS: MassARRAY assessed IL-33 DNA methylation and rs4742170 SNP; ELISA measured serum IL-4, IL-5, IL-13. Correlation analysis was conducted between DNA methylation, immune factors, and SNP, with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to CpG Islands

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Interleukin-13

Share to Interleukin-33

Share to Th2 Cells

Share to Tobacco Smoke Pollution

Source

Identifiers

PMID: 41702083
DOI: 10.1016/j.intimp.2026.116357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study between IL-33 gene DNA methylation and Pediatric asthma.PMID 41702083Read ↗

IL-33 gene variants and protein expression in pediatric Tunisian asthmatic patients.Semantic proximity Read ↗

IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population.Semantic proximity Read ↗

Genetics and Epigenetics in Asthma.Semantic proximity Read ↗

Methylation Profiles of IL33 and CCL26 in Bronchial Epithelial Cells are Associated with AsthmaSemantic proximity Read ↗

Serum interleukin 33 levels and single nucleotide polymorphism rs1929992 in Egyptian patients with chronic asthma.Semantic proximity Read ↗

The Impact of Interleukin (IL)-33 Gene Polymorphisms and Environmental Factors on Risk of Asthma in the Iranian Population.Semantic proximity Read ↗

Asthma-associated genetic variants induce IL33 differential expression through a novel regulatory region.Semantic proximity Read ↗

The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 yearsSemantic proximity Read ↗

Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthmaSemantic proximity Read ↗

DNA methylation in childhood asthma: an epigenome-wide meta-analysisSemantic proximity Read ↗

IL-33 family members and asthma – bridging innate and adaptive immune responsesSemantic proximity Read ↗

A meta-analysis of IL-13 polymorphisms and pediatric asthma risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.