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Impact of Global DNA Methylation in Treatment Outcome of Colorectal Cancer Patients

18 Oct 2018

Abstract excerpt

Background: Global DNA methylation has an impact in cancer pathogenesis and progression. This study aimed at investigating the impact of global DNA methylation in treatment outcome of colorectal (CRC) patients. Patients and methods: Global DNA methylation was measured by LC/ MS/ MS in whole blood of 102, 48 and 32 Egyptian CRC patients at baseline and after 3 & 6 months of FP therapy respectively, in addition to...

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PMID: 30405408
DOI: 10.3389/fphar.2018.01173

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