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Study of Promoter Methylation Patterns of HOXA2, HOXA5, and HOXA6 and Its Clinicopathological Characteristics in Colorectal Cancer

21 May 2019

Abstract excerpt

Research on DNA methylation offers great potential for the identification of biomarkers that can be applied for assessing an individual’s risk for cancer. In this article, we try to find the ideal epigenetic genes involved in colorectal cancer (CRC) based on database and our cohort. The top 20 genes with an extremely high frequency of hypermethylation in CRC were identified in database. Remarkably, 3 HOXA genes...

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PMID: 31165042
DOI: 10.3389/fonc.2019.00394

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