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Article

Quantitative DNA methylation analysis for epigenotyping of colorectal cancer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015

Kaneda Atsushi, Yagi Koichi

Abstract excerpt

Accumulation of epigenetic alteration plays important roles in tumorigenesis. Aberrant DNA hypermethylation in gene promoter regions is a common epigenetic mechanism for silencing tumor suppressor genes in many types of cancer including colorectal cancer (CRC). By using quantitative methylation information, CRC can be classified into three distinct methylation epigenotypes with different genetic features,...

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Identifiers

PMID: 25421666
DOI: 10.1007/978-1-4939-1804-1_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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