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Research progress of DNA methylation in colorectal cancer (Review)

3 Jul 2024

Abstract excerpt

DNA methylation is one of the earliest and most significant epigenetic mechanisms discovered. DNA methylation refers, in general, to the addition of a methyl group to a specific base in the DNA sequence under the catalysis of DNA methyltransferase, with S‑adenosine methionine as the methyl donor, via covalent bonding and chemical modifications. DNA methylation is an important factor in inducing cancer. There are...

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PMID: 38963030
DOI: 10.3892/mmr.2024.13278

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