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Article

Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma

18 Sept 2018

Abstract excerpt

Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially expressed genes and metabolites according to reactive stroma content measured on the exact same prostate cancer tissue sample. Reactive stroma was evaluated using histopathology from 108 fresh...

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PMID: 30250137
DOI: 10.1038/s41598-018-32549-1

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