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Article

Histologic features of stromogenic carcinoma of the prostate (carcinomas with reactive stroma grade 3).

Human pathology - 1 May 2017

De Vivar Andrea Diaz, Sayeeduddin Mohammad, Rowley David, Cubilla Antonio, Miles Brian, Kadmon Dov, Ayala Gustavo

Abstract excerpt

Prostatic carcinoma, like many other carcinomas, generates a stromal reaction. This phenomenon is well established in the scientific literature. The normal parenchymal smooth muscle phenotype switches to a myofibroblastic phenotype in response to the presence of cancer cells, with an expansion of the extracellular matrix compartment. The amount of reactive stroma is a predictor of biochemical recurrence in both...

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PMID: 28315427
DOI: 10.1016/j.humpath.2017.02.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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