Article
NMR-based metabolomics analysis identifies discriminatory metabolic disturbances in tissue and biofluid samples for progressive prostate cancer.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2020
Zheng Hong, Dong Baijun, Ning Jie, Shao Xiaoguang, Zhao Liangcai, Jiang Qiaoying, Ji Hui, Cai Aimin, Xue Wei, Gao Hongchang
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is one of the most common cancers in men, but its metabolic characteristics during tumor progression are still far from being fully understood. METHODS: The metabolic profiles of matched tissue, serum and urine samples from the same patients were analyzed using a 1H NMR-based metabolomics approach. We identified several important metabolites that significantly altered at...
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