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Article

Radiogenomic profiling of prostate tumors prior to external beam radiotherapy converges on a transcriptomic signature of TGF-β activity driving tumor recurrence

2023-05-02

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>Background</h4> Patients with localized prostate cancer have historically been assigned to clinical risk groups based on local disease extent, serum prostate specific antigen (PSA), and tumor grade. Clinical risk grouping is used to determine the intensity of treatment with external beam radiotherapy (EBRT) and androgen deprivation therapy (ADT), yet a substantial proportion of pat...

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Literature Corpus work
84e2a153-7176-55c1-ace5-c3c8c9b20ea8
DOI
10.1101/2023.05.01.23288883
Open publication

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Radiogenomic profiling of prostate tumors prior to external beam radiotherapy converges on a transcriptomic signature of TGF-β activity driving tumor recurrenceDOI 10.1101/2023.05.01.23288883
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