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Metabolomic Profiling Identifies Biochemical Pathways Associated with Castration-Resistant Prostate Cancer

20 Dec 2013

Abstract excerpt

Despite recent developments in treatment strategies, castration-resistant prostate cancer (CRPC) is still the second leading cause of cancer-associated mortality among American men, the biological underpinnings of which are not well understood. To this end, we measured levels of 150 metabolites and examined the rate of utilization of 184 metabolites in metastatic androgen-dependent prostate cancer (AD) and CRPC...

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PMID: 24359151
DOI: 10.1021/pr401106h

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