Article
PNPLA3 Gene Polymorphisms in HCV/HIV-Coinfected Individuals.
Digestive diseases and sciences - 1 Nov 2018
Sherman Kenneth E, Rouster Susan D, Kang Minhee, Umbleja Triin, Sterling Richard, Butt Adeel A
Abstract excerpt
BACKGROUND AND AIMS: The patatin-like phospholipase domain-containing 3 (PNPLA3) gene has been associated with the development of alcoholic and nonalcoholic steatohepatitis. Using a newly developed and validated assay for PNPLA3, we explored the prevalence of gene polymorphisms in a cohort of HCV/HIV-coinfected individuals to determine whether there was an association with insulin resistance or hepatic fibrosis....
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