The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients.

doi:10.1371/journal.pone.0168265

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The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients.

PloS one - 1 Jan 2016

Núñez-Torres Rocío, Macías Juan, Mancebo María, Frías Mario, Dolci Giovanni, Téllez Francisco, Merino Dolores, Merchante Nicolás, Gómez-Mateos Jesús, Guaraldi Giovanni, Rivero-Juárez Antonio, Pineda Juan A, Real Luis M

Abstract excerpt

Contradictory data about the impact of the rs738409 steatosis-related polymorphism within PNPLA3 gene on liver fibrosis progression in HIV/hepatitis C virus (HIV/HCV)-coinfected patients have been reported. Our objective was to test whether this, and other polymorphisms previously related to fatty liver disease in HIV infection linked to SAMM50 or LPPR4 genes, influence liver fibrosis progression in...

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Identifiers

PMID: 27973562
DOI: 10.1371/journal.pone.0168265
PMCID: PMC5156377

Genes

PNPLA3
SAMM50

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Source receipt: pubmed, retrieved 7 Sept 2026.

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