Article
Impact of patatin-like phospholipase domain-containing 3 gene polymorphism (rs738409) on severity of liver disease in HIV/hepatitis C virus-coinfected patients.
AIDS (London, England) - 28 Jan 2016
Jiménez-Sousa María A, Berenguer Juan, García-Álvarez Mónica, Gutierrez-Rivas Mónica, Aldámiz-Echevarria Teresa, Tejerina Francisco, Diez Cristina, Vázquez-Morón Sonia, Resino Salvador
Abstract excerpt
OBJECTIVE: To analyze the association between patatin-like phospholipase domain-containing 3 gene (PNPLA3) rs738409 polymorphism and severity of liver disease in HIV/hepatitis C virus-coinfected patients. METHODS: We performed a cross-sectional study of 215 patients who underwent a liver biopsy. PNPLA3 rs738409 polymorphism was genotyped using GoldenGate assay. The outcome variables were as follows: advanced...
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