Impact of PNPLA3 variants on liver histology of 168 patients with HIV infection and chronic hepatitis C.

doi:10.1016/j.cmi.2015.11.025

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Article

Impact of PNPLA3 variants on liver histology of 168 patients with HIV infection and chronic hepatitis C.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Apr 2016

Sagnelli C, Merli M, Uberti-Foppa C, Hasson H, Cirillo G, Grandone A, Salpietro S, Minichini C, Del Giudice E M, Lazzarin A, Sagnelli E, Coppola N

Abstract excerpt

This study analysed the impact of PNPLA3 variants on liver histology of 168 HIV/hepatitis C virus (HCV)-coinfected patients who were naïve for HCV treatment. A athologist unaware of the patients' condition graded liver fibrosis and necroinflammation (Ishak) and steatosis (Kleiner). Patients were tested for PNPLA3 variants and genotyped for the PNPLA3 rs738409 C to G variant underlying the I148M substitution. All...

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Identifiers

PMID: 26806136
DOI: 10.1016/j.cmi.2015.11.025

Genes

PNPLA3

Variants

rs738409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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