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Induced Pluripotent Stem Cells Reveal Common Neurodevelopmental Genome Deprograming in Schizophrenia.

Results and problems in cell differentiation - 1 Jan 2000

Narla Sridhar T, Decker Brandon, Sarder Pinaki, Stachowiak Ewa K, Stachowiak Michal K

Abstract excerpt

Schizophrenia is a neurodevelopmental disorder characterized by complex aberrations in the structure, wiring, and chemistry of multiple neuronal systems. The abnormal developmental trajectory of the brain is established during gestation, long before clinical manifestation of the disease. Over 200 genes and even greater numbers of single nucleotide polymorphisms and copy number variations have been linked with...

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PMID: 30209658
DOI: 10.1007/978-3-319-93485-3_6

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