Article
Population level mitogenomics of long-lived bats reveals dynamic heteroplasmy and challenges the Free Radical Theory of Ageing.
Scientific reports - 11 Sept 2018
Jebb David, Foley Nicole M, Whelan Conor V, Touzalin Frédéric, Puechmaille Sebastien J, Teeling Emma C
Abstract excerpt
Bats are the only mammals capable of true, powered flight, which drives an extremely high metabolic rate. The "Free Radical Theory of Ageing" (FTRA) posits that a high metabolic rate causes mitochondrial heteroplasmy and the progressive ageing phenotype. Contrary to this, bats are the longest-lived order of mammals given their small size and high metabolic rate. To investigate if bats exhibit increased...
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