Article
Genome-Wide Variants Shared Between Smoking Quantity and Schizophrenia on 15q25 Are Associated With CHRNA5 Expression in the Brain.
Schizophrenia bulletin - 18 Jun 2019
Ohi Kazutaka, Kuwata Aki, Shimada Takamitsu, Kataoka Yuzuru, Yasuyama Toshiki, Uehara Takashi, Kawasaki Yasuhiro
Abstract excerpt
Cigarette smokers with schizophrenia consume more cigarettes than smokers in the general population. Schizophrenia and smoking quantity may have shared genetic liability. Genome-wide association studies (GWASs) of schizophrenia and smoking quantity have highlighted a biological pleiotropy in which a robust 15q25 locus affects both traits. To identify the genetic variants shared between these traits on 15q25, we...
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