Article
A meta-analysis of Italian and Estonian individuals shows an effect of common variants in HMGCR on blood apoB levels.
Biomarkers in medicine - 1 Aug 2019
Rosticci Martina, Pervjakova Natalia, Kaakinen Marika, Cicero Arrigo F, Feufer Arne P, Marullo Letizia, Mägi Reedik, Fischer Krista, Jiang Longda, D'Addato Sergio, Rizzoli Elisabetta, Massimo Gianmichele, Giovannini Marina, Angelini Sabrina, Hrelia Patrizia, Scapoli Chiara, Borghi Claudio, Prokopenko Inga
Abstract excerpt
Aim: The aim of the study was to explore the effects of variants at HMGCR-KIF6loci on a range of cardio-metabolic phenotypes. Methods: We analyzed the range of variants within Genetics in Brisighella Health Study and KIF6 genes using an additive genetic model on 18 cardiometabolic phenotypes in a sample of 1645 individuals from the Genetics in Brisighella Health Study and replicated in 10,662 individuals from the...
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