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Article

Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin.

Clinica chimica acta; international journal of clinical chemistry - 2 May 2010

Cerda Alvaro, Genvigir Fabiana D V, Arazi Simone S, Hirata Mario H, Dorea Egidio L, Bernik Marcia M S, Bertolami Marcelo C, Faludi Andre A, Hirata Rosario D C

Abstract excerpt

BACKGROUND: The SR-BI is a key component on the cholesterol metabolism. Polymorphisms in the SR-BI gene (SCARB1) were related with variations on plasma lipoprotein profile and other risk factors for cardiovascular disease. We tested the relationship of 3 SCARB1 single nucleotide polymorphisms (SNPs) with hypercholesterolemia in a Brazilian population and whether these variants can influence lipid-lowering...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20064494
DOI: 10.1016/j.cca.2010.01.002

Genes

SCARB1

Variants

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Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin.PMID 20064494Read ↗

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