Article
Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia.
Psychiatric genetics - 1 Oct 2018
Curtis David
Abstract excerpt
BACKGROUND: The polygenic risk score (PRS) for schizophrenia, derived from very large numbers of weakly associated genetic markers, has been repeatedly shown to be robustly associated with schizophrenia in independent samples and also with other diseases and traits. AIM: This study aims to explore the distribution of the schizophrenia PRS in subjects of different ancestry. METHODS: The schizophrenia PRS derived...
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