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Article

A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1.

Journal of lipid research - 1 Jan 2010

Lattka E, Eggers S, Moeller G, Heim K, Weber M, Mehta D, Prokisch H, Illig T, Adamski J

Abstract excerpt

Fatty acid desaturases (FADS) play an important role in the formation of omega-6 and omega-3 highly unsaturated fatty acids (HUFAs). The composition of HUFAs in the human metabolome is important for membrane fluidity and for the modulation of essential physiological functions such as inflammation...

Read the complete abstract on PubMed

Topics

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Share to ets-Domain Protein Elk-1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Share to STAT1 Transcription Factor

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Share to Sterol Regulatory Element Binding Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 19546342
DOI: 10.1194/jlr.M900289-JLR200
PMCID: PMC2789778

Genes

FADS2
ELK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19546342-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1.PMID 19546342Read ↗

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FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on HealthSemantic proximity Read ↗

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DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.Semantic proximity Read ↗

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