Article
Glucose metabolism and metabolic flexibility in blood platelets.
Journal of thrombosis and haemostasis : JTH - 1 Nov 2018
Aibibula M, Naseem K M, Sturmey R G
Abstract excerpt
Essentials The metabolic integration processes required for platelet activation are unclear. The metabolic plasticity of human platelets were investigated. Activated platelets exhibit a glycolytic phenotype while preserving mitochondrial function. Platelets can switch freely between glucose/glycogen and fatty acids to support aggregation. SUMMARY: Background Platelet activation is an energy-dependent process, but...
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