Article
Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2017
Fidler Trevor P, Middleton Elizabeth A, Rowley Jesse W, Boudreau Luc H, Campbell Robert A, Souvenir Rhonda, Funari Trevor, Tessandier Nicolas, Boilard Eric, Weyrich Andrew S, Abel E Dale
Abstract excerpt
OBJECTIVE: On activation, platelets increase glucose uptake, glycolysis, and glucose oxidation and consume stored glycogen. This correlation between glucose metabolism and platelet function is not well understood and even less is known about the role of glucose metabolism on platelet function in vivo. For glucose to enter a cell, it must be transported through glucose transporters. Here we evaluate the...
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