Mitochondrial metabolism as a determinant of heterogeneous platelet functional phenotypes: Implications for antiplatelet resistance.

Abstract excerpt

Platelets are increasingly recognized as a heterogeneous circulating cell population whose functional behavior cannot be fully explained by receptor-agonist signaling alone; instead, their bioenergetic state emerges as a molecular determinant that shapes both physiological hemostasis and disease-associated hyperreactivity. This review synthesizes evidence supporting energetic specialization in platelets, where...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood Platelets
• Share to Energy Metabolism