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Standard Protocols for Characterising Primary and In Vitro‐Generated Human Hepatocytes

1 Feb 2025

Abstract excerpt

Hepatocyte-like cells (HLCs) derived from pluripotent stem cells (PSCs) or direct reprogramming are an unlimited source of human hepatocytes for biomedical applications. HLCs are used to model human diseases, develop precise drugs and establish groundbreaking regenerative cell-based therapies. Primary human hepatocytes are the gold standard for studying human liver biology and pathology. However, their widespread...

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PMID: 39910642
DOI: 10.1111/jcmm.70390

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