Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy

22 Mar 2012

Abstract excerpt

Recent advances in the study of human hepatocytes derived from induced pluripotent stem cells (iPSC) represent new promises for liver disease study and drug discovery. Human hepatocytes or hepatocyte-like cells differentiated from iPSC recapitulate many functional properties of primary human hepatocytes and have been demonstrated as a powerful and efficient tool to model human liver metabolic diseases and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22441839
DOI: 10.1007/s13238-012-2918-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapyPMID 22441839Read ↗

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read ↗

The Use of Induced Pluripotent Stem Cells for the Study and Treatment of Liver DiseasesSemantic proximity Read ↗

Advances in generating liver cells from pluripotent stem cells as a tool for modeling liver diseasesSemantic proximity Read ↗

Pluripotent Stem Cell–Derived Hepatocytes: Potential and Challenges in PharmacologySemantic proximity Read ↗

Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug DiscoverySemantic proximity Read ↗

The Application of Induced Pluripotent Stem Cells Against Liver Diseases: An Update and a ReviewSemantic proximity Read ↗

Human Induced Pluripotent Stem Cells in HepatologySemantic proximity Read ↗

Advancements in Disease Modeling and Drug Discovery Using iPSC-Derived Hepatocyte-like CellsSemantic proximity Read ↗

New Approaches in the Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells toward HepatocytesSemantic proximity Read ↗

Differentiation of Hepatocytes from Pluripotent Stem CellsSemantic proximity Read ↗

Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential ApplicationsSemantic proximity Read ↗

Derivation and applications of human hepatocyte-like cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.