Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derivation and applications of human hepatocyte-like cells

26 Aug 2019

Abstract excerpt

Human hepatocyte-like cells (HLCs) derived from human pluripotent stem cells (hPSCs) promise a valuable source of cells with human genetic background, physiologically relevant liver functions, and unlimited supply. With over 10 years' efforts in this field, great achievements have been made. HLCs have been successfully derived and applied in disease modeling, toxicity testing and drug discovery. Large cohorts of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Liver physiology and pathology
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31523372
DOI: 10.4252/wjsc.v11.i8.535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derivation and applications of human hepatocyte-like cellsPMID 31523372Read ↗

Human Induced Pluripotent Stem Cells in HepatologySemantic proximity Read ↗

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapySemantic proximity Read ↗

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read ↗

Standard Protocols for Characterising Primary and In Vitro‐Generated Human HepatocytesSemantic proximity Read ↗

Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential ApplicationsSemantic proximity Read ↗

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.Semantic proximity Read ↗

Pluripotent Stem Cell–Derived Hepatocytes: Potential and Challenges in PharmacologySemantic proximity Read ↗

Defined and Scalable Generation of Hepatocyte-like Cells from Human Pluripotent Stem CellsSemantic proximity Read ↗

Defined and Scalable Generation of Hepatocyte-like Cells from Human Pluripotent Stem CellsSemantic proximity Read ↗

Production of hepatocytes from human pluripotent stem cells for cell-based therapySemantic proximity Read ↗

Differentiation of Hepatocytes from Pluripotent Stem CellsSemantic proximity Read ↗

Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug DiscoverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.