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Article

Presence of L701 M mutation in the FKS1 gene of echinocandin-susceptible Candida krusei isolates.

Diagnostic microbiology and infectious disease - 1 Dec 2018

Lallitto Fabiola, Prigitano Anna, Mangione Francesca, Piralla Antonio, Tamarozzi Francesca, Marone Piero, Cavanna Caterina

Abstract excerpt

Resistance of Candida krusei isolates to echinocandins, the recommended drugs to treat candidemia, has been associated with mutations in hot spot (HS) regions of the FKS1 gene or L701 M mutation in a region between HS1 and HS3 of FKS1. However, the role of L701 M mutation alone in causing reduced echinocandins susceptibility is still unclear. We analyzed a region between HS1 and HS3 of FKS1 of 25 C. krusei...

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Identifiers

PMID: 30131237
DOI: 10.1016/j.diagmicrobio.2018.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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