Article
Quick Detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans.
Journal of clinical microbiology - 1 Jul 2015
Dudiuk Catiana, Gamarra Soledad, Jimenez-Ortigosa Cristina, Leonardelli Florencia, Macedo Daiana, Perlin David S, Garcia-Effron Guillermo
Abstract excerpt
A rapid molecular-based assay for the detection of the Candida albicans FKS1 gene mutations responsible for resistance to echinocandin drugs was designed and evaluated. The assay consisted of a multiplexed PCR set of 5 tubes able to detect the most commonly described resistance mechanism, includi...
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